Product Name :
Syntrophin alpha 1 Recombinant Rabbit Monoclonal Antibody [JG35-62]
Predicted band size :
54 kDa
Observed band size :
54 kDa
Synonyms:
59 kDa dystrophin-associated protein A1 acidic component 1 antibody Acidic alpha 1 syntrophin antibody Alpha 1 syntrophin antibody Alpha-1-syntrophin antibody dJ1187J4.5 antibody Dystrophin associated protein A1 59kDa acidic component antibody LQT12 antibody OTTHUMP00000030650 antibody Pro-TGF-alpha cytoplasmic domain-interacting protein 1 antibody SNT1 antibody 展开
Function :
The syntrophins are PDZ-domain-containing proteins that facilitate the recruitment of signaling proteins such as NOS1 to the dystrophin-associated protein complex. The syntrophin family are structurally related proteins that contain multiple protein interaction motifs. Syntrophins associate directly with dystrophin, the product of the Duchenne muscular dystrophy locus, and its homologs. α-Syntrophin has an important role in synapse formation and in the organization of utrophin, acetylcholine receptor and acetylcholinester-ase at the neuromuscular synapse.760952-88-3 Data Sheet Specifically, NOS1 binds to α-Syntrophin at muscle sarcolemma. β2-Syntrophin is a modular adapter. In muscle cells, β2-Syntrophin interacts with members of the dystrophin family, which in-cludes utrophin.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human Syntrophin alpha 1 aa 1-49 / 505.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, FC, IF-Tissue
Coupling :
unconjugated
Clone number:
JG35-62
RRID:
AB_3070815
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.4-Cyanobenzaldehyde manufacturer Aliquot store at -20℃.PMID:33413029 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 54 kDa
Positive control :
SiHa cell lysate, NIH/3T3 cell lysate, human skeletal muscle tissue, rat skeletal muscle tissue, mouse colon tissue, human colon tissue, LOVO.