Herein, we show that anSMEcpe contains in addition to the cluster harbored by all radical SAM (RS) enzymes, two additional clusters, related to the radical SAM protein AtsB, which catalyzes…
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By {simply|merely|just|basically} adding water and sodium iodide (NaI) to chlorotrimethylsilane (TMSCl), promotion of a Vorbrüggen glycosylation en route to {essential|important|crucial|vital|necessary|critical} HIV drugs emtricitabine (FTC) and lamivudine (3TC) is {achieved|accomplished}. TMSCl-NaI…
The conformational {changes|modifications|adjustments|alterations} {in a|inside a|within a} sugar moiety along the hydrolytic pathway are {key|important|crucial|essential} {to understand|to know} the mechanism of glycoside hydrolases (GHs) and to {design|style|design and style} new…
Simulation of optical spectra {is essential|is crucial} to molecular characterization and, in {many|numerous|several|a lot of|quite a few|lots of} {cases|instances|circumstances|situations}, {critical|crucial|vital|essential|important} for interpreting experimental spectra. {The most|Probably the most|Essentially the most|One…