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Stereochemical engineering of a peptide macrocycle allosteric inhibitor of phospho-Akt2 controls cell penetration by fine-tuning macrocycle-cell membrane interactions

Chemexpress September 27, 2024 0 Comments

We report the {development|improvement} of a cell-penetrant cyclic loop biligand that selectively binds, in vitro, {to the|towards the|for the} phosphorylated Ser474 {site|website|web site|internet site|web-site|web page} of Protein Kinase B (p-Akt2)…

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Selective extraction of biomolecules {using|utilizing|making use of|employing|working with|applying} a bidirectional flow filter

Chemexpress September 27, 2024 0 Comments

We present a microfluidic device for selective separation and extraction of molecules {based|primarily based} on their diffusivity. The separation relies on electroosmotically-driven bidirectional flows in which {high|higher} diffusivity species {experience|encounter|expertise|knowledge|practical…

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Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides

Chemexpress September 27, 2024 0 Comments

Sulfur-FluorideExchange (SuFEx) {is the|will be the|may be the|would be the|could be the|is definitely the} new generation click chemistry transformation exploitingthe {unique|distinctive|special|exclusive|exceptional|one of a kind} properties of S-F bonds and their…

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Alcohol Assisted Solution-Combustion {Technique|Method|Approach|Strategy} for the Synthesis of Phase-Pure BaSnO3 Nanoparticles at 130 °C

Chemexpress September 27, 2024 0 Comments

Lowering the synthesis temperature to {obtain|acquire|get|receive} phase pure BaSnO3, {which is|that is|which can be} the host material for {high|higher} figure-of-merit (FOM) perovskite transparent conductors (TCs), can expand the horizons for…

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Electrochemical {Studies|Research} of Chlorine Containing Silanes

Chemexpress September 26, 2024 0 Comments

The reduction potentials of a series of mono-, di- and trichloro alkyl and aryl substituted silanes was investigated by cyclic voltammetry. It was shown that chlorosilanes {can be|may be|could be|might…

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2-Aminopyridine-5-sulfonic Acid (CAS 16250-08-1)

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2-Amino Nevirapine (CAS 284686-15-3)

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2-Aminobenzothiazole (CAS 136-95-8)

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2-Amino-6-bromopurine (CAS 82499-03-4)

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