Product Name :
mSin3A Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
AW553200 antibody DKFZP434K2235 antibody FLJ90319 antibody Histone deacetylase complex subunit Sin 3a antibody Histone deacetylase complex subunit Sin3a antibody KIAA0700 antibody Kiaa4126 antibody mKIAA4126 antibody Paired amphipathic helix protein Sin 3a antibody Paired amphipathic helix protein Sin3a antibody 展开
Function :
Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation.1286754-61-7 Chemscene Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation.Price of 870483-68-4 Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression (By similarity).PMID:33660564 Required for cortical neuron differentiation and callosal axon elongation (By similarity).
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within human mSin3A aa 1-50.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
AB_3073455
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
145 kDa
Positive control :
HL-60 cell lysate, A549 cell lysate, Siha cell lysate.