Product Name :
SMG5 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Protein SMG5 EST1-like protein B LPTS-RP1 LPTS-interacting protein SMG-5 homolog hSMG-5 SMG5 EST1B KIAA1089 EST1 like protein B antibody 展开
Function :
Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within human SMG5 aa 800-1,000.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3071332
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.152754-55-7 Chemscene Aliquot store at -20℃.2-(Tributylstannyl)pyridine Price Avoid repeated freeze / thaw cycles.PMID:33666796
Storage buffer solution:
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
114 kDa
Positive control :
Jurkat cell lysate, Hela cell lysate, 293 cell lysate, THP-1 cell lysate, mouse testis tissue lysates, rat testis tissue lysates, Hela.