Product Name :
Tripeptidyl peptidase II Recombinant Rabbit Monoclonal Antibody [JE75-27]
Predicted band size :
138 kDa
Observed band size :
138 kDa
Synonyms:
TPP II antibody TPP2 antibody Tripeptidyl aminopeptidase antibody Tripeptidyl peptidase 2 antibody Tripeptidyl peptidase II antibody
Function :
Cytosolic tripeptidyl-peptidase that releases N-terminal tripeptides from polypeptides and is a component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. It plays an important role in intracellular amino acid homeostasis. The limitation of proteolytic products to tripeptides is achieved by tailoring the size of the substrate-binding cleft: the two negatively charged residues Glu-305 and Glu-331 that are blocking position P4 limit the number of residues that can be accommodated in the binding cleft and thus create a molecular ruler.Methyl 6-oxopiperidine-3-carboxylate manufacturer At the same time, they orient substrates so that the tripeptides are removed exclusively from the N-terminus.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within Human Tripeptidyl peptidase II aa 881-1,180 / 1,249.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, IF-Cell, FC
Coupling :
unconjugated
Clone number:
JE75-27
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.1-(2-Fluoroethyl)azetidin-3-amine Order 4), 0.PMID:33605198 05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 138 kDa
Positive control :
HeLa cell lysate, HEK-293 cell lysate, SW620 cell lysate, RPMI 8226 cell lysate, NIH/3T3 cell lysate, F9 cell lysate, C6 cell lysate, SW620, NIH/3T3, human colon cancer tissue, human testis tissue, human liver tissue, mouse liver tissue, rat liver tissue, C6.