Product Name :
Sortilin Recombinant Rabbit Monoclonal Antibody [JE60-00]
Predicted band size :
92 kDa
Observed band size :
100 kDa
Synonyms:
100 kDa NT receptor antibody Glycoprotein 95 antibody Gp 95 antibody Gp95 antibody LDLCQ6 antibody Neurotensin receptor 3 antibody NT 3 antibody NT3 antibody NTR 3 antibody NTR3 antibody 展开
Function :
Sortilin (SORT1) is a protein that in humans is encoded by the SORT1 gene on chromosome 1. This protein is a type I membrane glycoprotein in the vacuolar protein sorting 10 protein (Vps10p) family of sorting receptors. While it is ubiquitously expressed in many tissues, sortilin is most abundant in the central nervous system. At the cellular level, sortilin functions in protein transport between the Golgi apparatus, endosome, lysosome, and plasma membrane, leading to its involvement in multiple biological processes such as glucose and lipid metabolism as well as neural development and cell death. Moreover, the function and role of sortilin is now emerging in several major human diseases such as hypertension, atherosclerosis, coronary artery disease, Alzheimer’s disease, and cancer. The SORT1 gene also contains one of 27 loci associated with increased risk of coronary artery disease.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within Human Sortilin aa 601-800 / 831.
Species reactivity:
Human
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
JE60-00
RRID:
AB_3096726
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.2-Bromo-1-cyclohexylethan-1-one manufacturer Aliquot store at -20℃.3-Hydroxy-5-methoxybenzaldehyde Price Avoid repeated freeze / thaw cycles.PMID:33539714
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 92 kDa
Positive control :
SK-MEL-28 cell lysate, human lung tissue lysate, human kidney tissue lysate, human liver tissue lysate, SH-SY5Y cell lysate, human brain tissue lysate, human brain tissue.