Product Name :
SATB2 Recombinant Rabbit Monoclonal Antibody [JM52-44]
Predicted band size :
83 kDa
Observed band size :
83 kDa
Synonyms:
DNA binding protein SATB2 antibody DNA-binding protein SATB2 antibody FLJ21474 antibody FLJ32076 antibody GLSS antibody KIAA1034 antibody MGC119474 antibody MGC119477 antibody SATB family member 2 antibody SATB homeobox 2 antibody 展开
Function :
SATB2 (Special AT-rich sequence-binding protein 2) is a nuclear matrix protein that influences craniofacial formation mechanisms, such as jaw and palate development, and is part of a transcriptional network regulating skeletal development and osteoblast differentiation. Highly expressed in adult and fetal brain, SATB2 contains two CUT DNA-binding domains and one homeobox domain and is closely related to SATB1, a transcriptional repressor. SATB2 is thought to bind to matrix-attachment regions (MARs) and regulate MAR-dependent transcription of various genes, including HoxA2 and ATF4 (CREB-2), involved in skeletal development.157327-48-5 supplier Functioning as both a transcriptional activator and repressor, SATB2 can also act as a protein scaffold that can enhance the activity of other DNA-binding proteins.4,6-Dichloro-2-(ethoxymethyl)pyrimidine Order Defects in the gene encoding SATB2 are the cause of cleft palate manifested in conjunction with severe mental retardation.PMID:33715076
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human SATB2 238-287 / 733.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, FC, ChIP
Coupling :
unconjugated
Clone number:
JM52-44
RRID:
AB_3070623
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 83 kDa
Positive control :
THP-1 cell lysate, Saos-2 cell lysate, C6 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, PC-12, SH-SY5Y, LOVO, human colon carcinoma tissue, mouse brain tissue, rat brain tissue, rat large intestine tissue.