An optimized catalytic protocol for enantio- and diastereoselective reduction of racemic α-CF3, α-SCF3 and α-OCF3 aryl ketones is described. The reaction {involves|entails|requires|includes} a dynamic kinetic resolution (DKR) {based|primarily based} on…
Human immunodeficiency virus 1 (HIV-1) protease {is a|is really a|is actually a|can be a|is often a|is usually a} homo-dimeric aspartic protease {essential|important|crucial|vital|necessary|critical} for replication of HIV. The HIV-1 protease {is…
Cluster expansion (CE) {is a|is really a|is actually a|can be a|is often a|is usually a} {powerful|potent|effective|strong|highly effective} theoretical tool to study the configuration-dependent properties of substitutionally disordered systems. {Typically|Usually|Normally|Generally|Commonly|Ordinarily}, a…
A computationally {faster|quicker|more quickly|more rapidly} and {reliable|dependable|trustworthy|reputable|trusted} modelling {approach|method|strategy} {called|known as|referred to as|named} a physics-based artificial neural network framework for adsorption and chromatography emulation (PANACHE) is {developed|created}. PANACHE {uses|utilizes|makes use…
Dynamic nuclear polarization (DNP) {using|utilizing|making use of|employing|working with|applying} transient electron spin polarization generated by photoexcitation can {improve|enhance|boost|increase|strengthen} nuclear magnetic resonance (NMR) sensitivity far beyond the thermal equilibrium limit for {analysis|evaluation}…