Predicting molecular properties remains a difficult job with numerous possible applications, notably in drug discovery. Lately, the improvement of deep studying, combined with increasing amounts of information, has offered potent…
New electrochemical ammonia (NH3) synthesis technologies are of interest as a complementary route for the Haber-Bosch (HB) method for distributed fertilizer generation, and towards exploiting ammonia as a zero-carbon fuel…
Vitamin B12 derivatives catalyze a wide variety of organic transformations, but B12-dependent enzymes are underutilized in biocatalysis relative to other metalloenzymes. In this study, we engineered a variant of your…
Nitrate and nitrite are crucial elements on the international nitrogen cycle. As such, Nature has evolved proteins as biological supramolecular hosts for the recognition, translocation, and transformation of both nitrate…
Within this manuscript we describe a modular pathwayto synthesize biologically relevant (鈥?-trans-螖8-THCderivatives, which can be utilized to modulate the pharmacologically important CB1and CB2 receptors. This pathway includes a one-pot Friedel-Craftsalkylation/cyclization…